Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
phoPAlkaline phosphatase synthesis transcriptional regulatory protein; Similar to SUB0552, 50.847% identity (52.402% ungapped) in 236 aa overlap (1-232:1-233). (240 aa)    
Predicted Functional Partners:
phoR
Similar to the C-terminal region of Bacillus subtilis alkaline phosphatase synthesis sensor protein PhoR UniProt:PHOR_BACSU (EMBL:AF008220) (579 aa) fasta scores: E()=2.8e-31, 36.164% id in 365 aa, and to the full length Streptococcus pneumoniae histidine kinase PnpS UniProt:Q9X4S9_STRPN (EMBL:AF118229) (422 aa) fasta scores: E()=2.3e-77, 57.494% id in 407 aa.
 0.997
SUB0202
Sensor histidine kinase.
 
 0.880
SUB0191
Sensor histidine kinase.
 
 
 0.878
vicK
Sensor histidine kinase.
 
 0.871
csrS
Sensor histidine kinase.
 
 
 0.826
ciaH
Sensor histidine kinase.
 
 
 0.809
SUB0916
Sensor histidine kinase.
 
 
 0.781
SUB0569
Putative lipoprotein.
  
  
 0.687
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.629
parE
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
      
 0.628
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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