STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB0651Haloacid dehalogenase-like hydrolase; Similar to Shigella flexneri phosphoserine phosphatase SerB UniProt:SERB_ECOLI (EMBL:AE016993) (322 aa) fasta scores: E()=2.9e-24, 46.117% id in 206 aa, and to the full length Streptococcus thermophilus (strain ATCC BAA-250/LMG 18311) phosphoserine phosphatase SerB UniProt:Q5M3B3_STRTR (215 aa) fasta scores: E()=2.2e-46, 68.224% id in 214 aa. (219 aa)    
Predicted Functional Partners:
serC
Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.949
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.937
sdhB
Putative L-serine dehydratase, beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.916
sdhA
Putative L-serine dehydratase, alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.916
cysE
Serine acetyltransferase.
    
 0.834
SUB1030
Putative acetyltransferase.
    
 0.834
SUB0652
Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein.
       0.782
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
     
 0.639
hisC
Putative histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
  
 0.620
SUB0648
Putative haloacid dehalogenase-like hydrolase.
  
  
 0.513
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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