STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gorGlutathione reductase. (449 aa)    
Predicted Functional Partners:
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.945
pdhB
Putative pyruvate dehydrogenase E1 component, beta subunit.
 
 0.914
acoL
HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.
 
0.833
gshA
Putative glutamate--cysteine ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
   
 0.780
pdhA
Putative pyruvate dehydrogenase E1 component, alpha subunit.
 
 
 0.739
tpx
Putative thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.703
SUB0718
Conserved hypothetical protein; Belongs to the UPF0342 family.
       0.695
SUB1360
NADH:flavin oxidoreductase / NADH oxidase family protein.
 
 
 0.657
galE
UDP-glucose 4-epimerase (pseudogene); HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 9e-139.
 
 0.644
SUB0745
Pyridine nucleotide-disulphide oxidoreductase family protein.
  
 
 0.634
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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