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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB0728LysR family regulatory protein; Belongs to the LysR transcriptional regulatory family. (304 aa)    
Predicted Functional Partners:
SUB0730
Putative RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.807
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.800
SUB1393
LysR family regulatory protein; Belongs to the LysR transcriptional regulatory family.
  
     0.609
rpmA
50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
  
 0.578
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.537
SUB0726
Conserved hypothetical protein.
       0.518
pyrR
PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
       0.494
SUB0808
Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.474
pyrP
Uracil permease.
     
 0.471
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.415
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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