Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUB0748DeoR family regulatory protein. (237 aa)    
Predicted Functional Partners:
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
 
  
 0.971
fruK
Putative 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.960
mur1.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase family protein.
       0.634
lacC2
Tagatose-6-phosphate kinase 2; Similar to SUB1455, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-310:1-311); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.618
SUB0747
Putative ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
    0.593
SUB0745
Pyridine nucleotide-disulphide oxidoreductase family protein.
       0.583
rimM
16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
       0.579
trmD
tRNA (Guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
       0.579
SUB0746
Putative membrane protein.
       0.559
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
    0.558
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (22%) [HD]