STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruKPutative 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (303 aa)    
Predicted Functional Partners:
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
 
 
 0.999
SUB0748
DeoR family regulatory protein.
 
  
 0.930
fba
Fructose-bisphosphate aldolase.
  
 
 0.923
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.912
fbp
Putative fructose-1,6-bisphosphatase.
    
 0.908
lacE2
Putative lactose-specific phosphotransferase system (PTS), IIBC component 2; Similar to SUB1450, 61.717% identity (62.050% ungapped) in 559 aa overlap (1-558:1-557).
  
  
 0.707
mtlF
Putative mannitol-specific phosphotransferase system (PTS), IIA component.
 
  
 0.658
mur1.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase family protein.
       0.590
pstI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.579
SUB0747
Putative ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.531
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.