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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruA-2Putative fructose-specific phosphotransferase system (PTS), IIABC component. (647 aa)    
Predicted Functional Partners:
fruK
Putative 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
ptsH
Histidine-containing phosphocarrier protein (HPr).
 
 
 0.995
pstI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.984
lacC1
Tagatose-6-phosphate kinase 1; Similar to SUB0795, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-311:1-310); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.982
lacC2
Tagatose-6-phosphate kinase 2; Similar to SUB1455, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-310:1-311); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.981
mtlF
Putative mannitol-specific phosphotransferase system (PTS), IIA component.
 
  
 0.977
fba
Fructose-bisphosphate aldolase.
  
 
 0.974
SUB0830
Transcription antiterminator (pseudogene); HMMPfam hit to PF00874, PRD domain, score 2.1e-14.
 
  
 0.963
scrA
Putative sucrose-specific phosphotransferase system (PTS), IIABC component.
 
  
 0.962
SUB1763
Sugar phosphotransferase system (PTS), IIABC component.
 
  
 0.959
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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