STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mvaDMevalonate diphosphate decarboxylase. (314 aa)    
Predicted Functional Partners:
mvaK2
Phosphomevalonate kinase.
 
 
 0.998
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.998
mvaK1
Putative surface-anchored 5'-nucleotidase (pseudogene); HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 9.5e-11.
 
  
 0.991
mvaS
3-hydroxy-3-methylglutaryl coenzyme A synthase.
 
 
 0.945
fps
Putative geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.944
mvaA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.841
SUB0914
Putative NUDIX hydrolase.
  
  
 0.515
lysS
lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
    0.480
SUB0108
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.473
atoB2
acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.449
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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