STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (330 aa)    
Predicted Functional Partners:
mvaD
Mevalonate diphosphate decarboxylase.
 
  
 0.995
mvaK2
Phosphomevalonate kinase.
  
 0.974
mvaK1
Putative surface-anchored 5'-nucleotidase (pseudogene); HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 9.5e-11.
 
  
 0.962
fps
Putative geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.928
mvaA
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
   
 0.859
mvaS
3-hydroxy-3-methylglutaryl coenzyme A synthase.
 
  
 0.817
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
     
 0.565
SUB1360
NADH:flavin oxidoreductase / NADH oxidase family protein.
  
  
 0.518
penA
HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 2.6e-27.
      
 0.510
mtnN
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.503
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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