Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
lacRConserved hypothetical protein (fragment); Probable gene remnant. Similar to the C-terminal region of Streptococcus pneumoniae (strain ATCC BAA-255/R6) hypothetical protein spr0959. UniProt:Q8CYS8_STRR6 (EMBL:AE008468) (198 aa) fasta scores: E()=7.6e-11, 50.000% id in 90 aa. (251 aa)    
Predicted Functional Partners:
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
 
  
 0.715
lacC2
Tagatose-6-phosphate kinase 2; Similar to SUB1455, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-310:1-311); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.704
lacD2
Tagatose 1,6-diphosphate aldolase 2; Similar to SUB1454, 75.460% identity (75.692% ungapped) in 326 aa overlap (1-326:1-325); and SUB0040, 75.000% identity (75.232% ungapped) in 324 aa overlap (3-326:4-326); Belongs to the aldolase LacD family.
     
 0.585
lacC1
Tagatose-6-phosphate kinase 1; Similar to SUB0795, 61.736% identity (61.935% ungapped) in 311 aa overlap (1-311:1-310); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.525
fruK
Putative 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.520
rpmGB
50S ribosomal protein L33 2; Belongs to the bacterial ribosomal protein bL33 family.
      
 0.500
rpmG-2
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
      
 0.500
lacA2
Galactose-6-phosphate isomerase LacA subunit 2; Similar to SUB1457, 74.286% identity (74.286% ungapped) in 140 aa overlap (1-140:1-140).
     
 0.493
lacB2
Galactose-6-phosphate isomerase LacB subunit 2; Similar to SUB1456, 77.778% identity (77.778% ungapped) in 171 aa overlap (1-171:1-171).
     
 0.479
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
      
 0.444
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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