Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB0825NAD-dependent malic enzyme. (385 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.968
pdhB
Putative pyruvate dehydrogenase E1 component, beta subunit.
  
 
 0.940
pyk
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.938
malP
Sodium-dependent malate transporter.
 
  
 0.932
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
 
 0.928
pta
Putative phosphate acetyltransferase.
 
  
 0.924
pdhA
Putative pyruvate dehydrogenase E1 component, alpha subunit.
  
 
 0.917
gcdB
Putative Na+-transporting glutaconyl-CoA decarboxylase beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.914
pfl
Formate acetyltransferase.
   
 
 0.911
SUB1584
Putative carboxylase subunit.
    
 0.907
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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