node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SUB0721 | SUB0808 | SUB0721 | SUB0808 | Putative cysteine desulfhydrase. | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | 0.999 |
SUB0721 | SUB0849 | SUB0721 | SUB0849 | Putative cysteine desulfhydrase. | Putative cysteine desulfurase. | 0.915 |
SUB0721 | csdB | SUB0721 | SUB0345 | Putative cysteine desulfhydrase. | Putative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.593 |
SUB0721 | dnaK | SUB0721 | SUB1504 | Putative cysteine desulfhydrase. | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.545 |
SUB0721 | iscU | SUB0721 | SUB0346 | Putative cysteine desulfhydrase. | NifU-like protein; In S. thermophilus iscU mutant displayed increased sensitivity to superoxide radicals compared to the wild type. IscU is likely to play a major role in oxidative stress defense, possibly resulting from its role in [Fe-S] cluster assembly and/or repair. | 0.967 |
SUB0721 | thiI | SUB0721 | SUB0722 | Putative cysteine desulfhydrase. | Putative thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.992 |
SUB0808 | SUB0721 | SUB0808 | SUB0721 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | Putative cysteine desulfhydrase. | 0.999 |
SUB0808 | SUB0849 | SUB0808 | SUB0849 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | Putative cysteine desulfurase. | 0.999 |
SUB0808 | csdB | SUB0808 | SUB0345 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | Putative cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.708 |
SUB0808 | dnaK | SUB0808 | SUB1504 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.625 |
SUB0808 | iscU | SUB0808 | SUB0346 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | NifU-like protein; In S. thermophilus iscU mutant displayed increased sensitivity to superoxide radicals compared to the wild type. IscU is likely to play a major role in oxidative stress defense, possibly resulting from its role in [Fe-S] cluster assembly and/or repair. | 0.750 |
SUB0808 | thiI | SUB0808 | SUB0722 | Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family. | Putative thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.458 |
SUB0847 | SUB0848 | SUB0847 | SUB0848 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.720 |
SUB0847 | SUB0849 | SUB0847 | SUB0849 | Conserved hypothetical protein. | Putative cysteine desulfurase. | 0.720 |
SUB0847 | SUB0851 | SUB0847 | SUB0851 | Conserved hypothetical protein. | Adenylate cyclase family protein. | 0.479 |
SUB0847 | prsA2 | SUB0847 | SUB0850 | Conserved hypothetical protein. | Putative ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.720 |
SUB0848 | SUB0847 | SUB0848 | SUB0847 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.720 |
SUB0848 | SUB0849 | SUB0848 | SUB0849 | Conserved hypothetical protein. | Putative cysteine desulfurase. | 0.886 |
SUB0848 | SUB0851 | SUB0848 | SUB0851 | Conserved hypothetical protein. | Adenylate cyclase family protein. | 0.565 |
SUB0848 | prsA2 | SUB0848 | SUB0850 | Conserved hypothetical protein. | Putative ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.800 |