| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SUB0210 | prmC | SUB0210 | SUB0872 | Conserved hypothetical protein; Belongs to the LOG family. | Putative methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.719 |
| SUB0320 | prmC | SUB0320 | SUB0872 | Conserved hypothetical protein; Belongs to the UPF0340 family. | Putative methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.729 |
| SUB0869 | SUB0873 | SUB0869 | SUB0873 | Putative 4-oxalocrotonate tautomerase. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.823 |
| SUB0869 | SUB0875 | SUB0869 | SUB0875 | Putative 4-oxalocrotonate tautomerase. | Conserved hypothetical protein. | 0.661 |
| SUB0869 | SUB0876 | SUB0869 | SUB0876 | Putative 4-oxalocrotonate tautomerase. | Putative membrane protein; Similar to Pneumococcal vaccine antigen A protein. | 0.677 |
| SUB0869 | glyA | SUB0869 | SUB0874 | Putative 4-oxalocrotonate tautomerase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.691 |
| SUB0869 | prfA | SUB0869 | SUB0871 | Putative 4-oxalocrotonate tautomerase. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.689 |
| SUB0869 | prmC | SUB0869 | SUB0872 | Putative 4-oxalocrotonate tautomerase. | Putative methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.689 |
| SUB0869 | tdk | SUB0869 | SUB0870 | Putative 4-oxalocrotonate tautomerase. | Putative thymidine kinase. | 0.681 |
| SUB0873 | SUB0869 | SUB0873 | SUB0869 | Conserved hypothetical protein; Belongs to the SUA5 family. | Putative 4-oxalocrotonate tautomerase. | 0.823 |
| SUB0873 | SUB0875 | SUB0873 | SUB0875 | Conserved hypothetical protein; Belongs to the SUA5 family. | Conserved hypothetical protein. | 0.793 |
| SUB0873 | SUB0876 | SUB0873 | SUB0876 | Conserved hypothetical protein; Belongs to the SUA5 family. | Putative membrane protein; Similar to Pneumococcal vaccine antigen A protein. | 0.804 |
| SUB0873 | glyA | SUB0873 | SUB0874 | Conserved hypothetical protein; Belongs to the SUA5 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.941 |
| SUB0873 | prfA | SUB0873 | SUB0871 | Conserved hypothetical protein; Belongs to the SUA5 family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.854 |
| SUB0873 | prmC | SUB0873 | SUB0872 | Conserved hypothetical protein; Belongs to the SUA5 family. | Putative methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.876 |
| SUB0873 | tdk | SUB0873 | SUB0870 | Conserved hypothetical protein; Belongs to the SUA5 family. | Putative thymidine kinase. | 0.823 |
| SUB0875 | SUB0869 | SUB0875 | SUB0869 | Conserved hypothetical protein. | Putative 4-oxalocrotonate tautomerase. | 0.661 |
| SUB0875 | SUB0873 | SUB0875 | SUB0873 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the SUA5 family. | 0.793 |
| SUB0875 | SUB0876 | SUB0875 | SUB0876 | Conserved hypothetical protein. | Putative membrane protein; Similar to Pneumococcal vaccine antigen A protein. | 0.860 |
| SUB0875 | glyA | SUB0875 | SUB0874 | Conserved hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.835 |