Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SUB0940Similar to Bacillus pseudofirmus cardiolipin synthetase Cls UniProt:CLS_BACPF (EMBL:U88888) (503 aa) fasta scores: E()=2.1e-52, 31.944% id in 504 aa, and to Streptococcus pyogenes (serotype M6) cardiolipin synthetase Cls UniProt:Q5XC13_STRP6 (EMBL:CP000003) (525 aa) fasta scores: E()=9.2e-164, 78.812% id in 505 aa. CDS is truncated at the N-terminus in comparison to some orthologues. Similarity extends beyond the marked translational start, but the extended CDS lacks an appropriate translational start site. Possible pseudogene; Belongs to the phospholipase D family. Cardiolipin synthas [...] (505 aa)    
Predicted Functional Partners:
SUB0460
Putative membrane protein; Possible gene remnant. Weakly similar to Photorhabdus luminescens (subsp. laumondii) ribose transport system permease protein RbsC UniProt:Q7NA78_PHOLL (EMBL:BX571859) (323 aa) fasta scores: E()=3.8, 30.928% id in 97 aa.
  
  
 0.647
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
 0.646
pgsA
Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.646
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
  
  
 0.610
SUB0740
Putative glycerophosphodiester phosphodiesterase.
     
 0.576
SUB0941
Conserved hypothetical protein.
       0.543
fhs1
Formate--tetrahydrofolate ligase 1; Belongs to the formate--tetrahydrofolate ligase family.
     
 0.541
SUB0253
Putative phosphatidate cytidylyltransferase; Belongs to the CDS family.
     
 0.539
comEC
Putative competence protein.
   
 
 0.502
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.489
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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