STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB0940Similar to Bacillus pseudofirmus cardiolipin synthetase Cls UniProt:CLS_BACPF (EMBL:U88888) (503 aa) fasta scores: E()=2.1e-52, 31.944% id in 504 aa, and to Streptococcus pyogenes (serotype M6) cardiolipin synthetase Cls UniProt:Q5XC13_STRP6 (EMBL:CP000003) (525 aa) fasta scores: E()=9.2e-164, 78.812% id in 505 aa. CDS is truncated at the N-terminus in comparison to some orthologues. Similarity extends beyond the marked translational start, but the extended CDS lacks an appropriate translational start site. Possible pseudogene; Belongs to the phospholipase D family. Cardiolipin synthas [...] (505 aa)    
Predicted Functional Partners:
iscU
NifU-like protein; In S. thermophilus iscU mutant displayed increased sensitivity to superoxide radicals compared to the wild type. IscU is likely to play a major role in oxidative stress defense, possibly resulting from its role in [Fe-S] cluster assembly and/or repair.
   
 
 0.643
comEC
Putative competence protein.
   
 
 0.594
SUB0460
Putative membrane protein; Possible gene remnant. Weakly similar to Photorhabdus luminescens (subsp. laumondii) ribose transport system permease protein RbsC UniProt:Q7NA78_PHOLL (EMBL:BX571859) (323 aa) fasta scores: E()=3.8, 30.928% id in 97 aa.
  
  
 0.573
SUB0941
Conserved hypothetical protein.
       0.545
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
  
  
 0.532
SUB0740
Putative glycerophosphodiester phosphodiesterase.
     
 0.510
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
 0.503
pgsA
Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.445
fhs1
Formate--tetrahydrofolate ligase 1; Belongs to the formate--tetrahydrofolate ligase family.
     
 0.430
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.402
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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