Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtlAPutative mannitol-specific phosphotransferase system (PTS), IIBC component; N-terminal region is similar to SUB0289, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-471:1-466). (588 aa)    
Predicted Functional Partners:
mtlF
Putative mannitol-specific phosphotransferase system (PTS), IIA component.
 
 0.999
mtlD
Mannitol-1-phosphate 5-dehydrogenase.
 
 
 0.998
mtlD-2
Putative mannitol-1-phosphate 5-dehydrogenase.
 
 
 0.988
mtlR
Putative transcriptional regulator.
 
  
 0.968
SUB0288
Sugar phosphotransferase system (PTS), IIA component.
 
 
 0.952
ptsH
Histidine-containing phosphocarrier protein (HPr).
   
 0.936
SUB0289
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; Similar to the N-terminal region of Escherichia coli PTS system, mannitol-specific IIABC component MtlA UniProt:PTMA_ECOLI (EMBL:ECUW76) (637 aa) fasta scores: E()=6.9e-92, 51.502% id in 466 aa; Similar to the N-terminal region of SUB0997, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-466:1-471).
  
  
 
0.904
SUB0993
PhnA protein.
     
 0.856
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.705
SUB0530
Transcriptional regulator (antiterminator).
 
  
 0.647
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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