Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hasB2UDP-glucose 6-dehydrogenase 2; Similar to SUB1696, 58.293% identity (59.900% ungapped) in 410 aa overlap (3-411:2-401). (411 aa)    
Predicted Functional Partners:
SUB1028
Putative nucleotide sugar epimerase.
 
 0.985
rmlA
Glucose-1-phosphate thymidyl transferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.980
hasC
UTP--glucose-1-phosphate uridylyltransferase.
  
 0.963
SUB1036
Putative galacturonic acid acetylase (fragment); Probable gene remnant. Similar to an internal region of Streptococcus pneumoniae Cap1F galacturonic acid acetylase UniProt:P96477_STRPN (EMBL:SPZ83335) (183 aa) fasta scores: E()=1e-06, 38.889% id in 72 aa.
  
  
 0.914
SUB1031
Putative exopolysaccharide biosynthesis protein.
  
  
 0.912
gcaD
Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...]
    
 0.902
hasB1
UDP-glucose 6-dehydrogenase 1; Similar to SUB1027, 58.293% identity (59.900% ungapped) in 410 aa overlap (2-401:3-411).
  
  
 
0.902
rmlC
Putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase.
  
  
 0.873
SUB1032
Hypothetical protein.
  
  
 0.840
uidA
Putative beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
     
 0.806
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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