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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (226 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
  
 
 0.995
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.954
RPE
Putative ribulose-phosphate 3-epimerase; Similar to the C-terminal region of Spinacia oleracea (Spinach) ribulose-phosphate 3-epimerase, chloroplast precursor RPE (ec 5.1.3.1) (pentose-5-phosphate 3-epimerase) UniProt:RPE_SPIOL (EMBL:AF070941) (285 aa) fasta scores: E()=2.9e-21, 38.614% id in 202 aa.
 
 0.948
prsA1
Ribose-phosphate pyrophosphokinase 1; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.943
rpe
Putative ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.942
tkt2
Putative transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.937
SUB0199
6-phosphogluconate dehydrogenase family protein; Similar to the N-terminal regions of Saccharomyces cerevisiae (Baker's yeast) GND2 6-phosphogluconate dehydrogenase, decarboxylating 2 UniProt:6PG2_YEAST (492 aa) fasta scores: E()=3e-24, 37.209% id in 301 aa, and Escherichia coli 6-phosphogluconate dehydrogenase, decarboxylating Gnd UniProt:6PG9_ECOLI (468 aa) fasta scores: E()=3.1e-22, 36.333% id in 300 aa.
 
  
 0.929
prsA2
Putative ribose-phosphate pyrophosphokinase 2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.918
pgmA
Putative phosphomannomutase.
    
 0.913
SUB1757
Putative transketolase subunit; Similar to the C-terminal region of Homo sapiens (Human) transketolase TKT UniProt:TKT_HUMAN (EMBL:HSTRANSKE) (623 aa) fasta scores: E()=2.7e-17, 27.213% id in 305 aa.
    
 0.906
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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