STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhBPutative pyruvate dehydrogenase E1 component, beta subunit. (333 aa)    
Predicted Functional Partners:
acoL
HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.
 
 0.999
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
pdhA
Putative pyruvate dehydrogenase E1 component, alpha subunit.
 0.999
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.969
SUB0825
NAD-dependent malic enzyme.
  
 
 0.940
pfl
Formate acetyltransferase.
   
 
 0.937
pyk
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.922
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.917
gor
Glutathione reductase.
 
 0.914
SUB1584
Putative carboxylase subunit.
    
  0.906
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.