Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rmlAGlucose-1-phosphate thymidyl transferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (289 aa)    
Predicted Functional Partners:
rmlB
Putative dTDP-glucose-4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
 0.999
rmlC
Putative dTDP-4-keto-6-deoxyglucose-3,5-epimerase.
 
  
 0.999
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
  
 0.987
hasB2
UDP-glucose 6-dehydrogenase 2; Similar to SUB1696, 58.293% identity (59.900% ungapped) in 410 aa overlap (3-411:2-401).
  
 
 0.980
hasB1
UDP-glucose 6-dehydrogenase 1; Similar to SUB1027, 58.293% identity (59.900% ungapped) in 410 aa overlap (2-401:3-411).
  
 
 0.980
SUB1036
Putative galacturonic acid acetylase (fragment); Probable gene remnant. Similar to an internal region of Streptococcus pneumoniae Cap1F galacturonic acid acetylase UniProt:P96477_STRPN (EMBL:SPZ83335) (183 aa) fasta scores: E()=1e-06, 38.889% id in 72 aa.
  
  
 0.964
hasC
UTP--glucose-1-phosphate uridylyltransferase.
 
 
0.926
pgmA
Putative phosphomannomutase.
  
 
 0.922
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 
0.901
SUB0663
Putative glycogen biosynthesis protein.
    
  0.901
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.