Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
copZPutative transposase (fragment); Probable gene remnant. Similar to the C-terminal region of Escherichia coli putative transposase InsK for insertion sequence element IS150 UniProt:INSK_ECOLI (EMBL:ECUW76) (283 aa) fasta scores: E()=4.7e-08, 34.615% id in 130 aa. (77 aa)    
Predicted Functional Partners:
SUB1181
Putative copper importing ATPase.
 
 
 0.960
SUB1182
Hypothetical protein.
 
   
 0.888
SUB1183
Crp family regulatory protein.
 
    0.874
SUB1266
Putative cation-transporting ATPase.
 
 
 0.716
copY
Putative negative regulator of copper transport operon.
  
  
 0.716
copA
Copper-transporting ATPase.
  
 
 0.666
SUB1184
Hypothetical protein; Doubtful CDS.
     
 0.563
SUB0808
Pyridine nucleotide-disulphide oxidoreductase family protein; N-terminal region is similar to Methanococcus jannaschii putative NADH oxidase UniProt:NAOX_METJA (EMBL:MJU67512) (463 aa) fasta scores: E()=2.2e-44, 34.667% id in 450 aa. Full length CDS is similar to Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase UniProt:Q8A513_BACTN (EMBL:AE016936) (826 aa) fasta scores: E()=2.2e-125, 47.545% id in 835 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.460
SUB0477
Conserved hypothetical protein (pseudogene); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
   0.406
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (12%) [HD]