STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pstIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)    
Predicted Functional Partners:
ptsH
Histidine-containing phosphocarrier protein (HPr).
 
 0.999
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
 
  
 0.984
SUB0830
Transcription antiterminator (pseudogene); HMMPfam hit to PF00874, PRD domain, score 2.1e-14.
 
 0.946
SUB1763
Sugar phosphotransferase system (PTS), IIABC component.
 
 0.940
SUB0236
Putative glucose-specific phosphotransferase system (PTS), IIABC component.
 
 0.938
scrA
Putative sucrose-specific phosphotransferase system (PTS), IIABC component.
 
 0.909
ptsK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
 
   
 0.610
fruK
Putative 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.579
gapN
Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase.
     
 0.556
SUB1761
Putative PTS multi-domain regulator.
 
 
 
 0.506
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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