Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ptsHHistidine-containing phosphocarrier protein (HPr). (87 aa)    
Predicted Functional Partners:
pstI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
 
 
 0.993
manL
Putative mannose-specific phosphotransferase system (PTS), IIAB component.
  
 0.990
SUB0830
Transcription antiterminator (pseudogene); HMMPfam hit to PF00874, PRD domain, score 2.1e-14.
  
 0.984
scrA
Putative sucrose-specific phosphotransferase system (PTS), IIABC component.
  
 0.984
SUB1763
Sugar phosphotransferase system (PTS), IIABC component.
  
 0.984
mtlF
Putative mannitol-specific phosphotransferase system (PTS), IIA component.
   
 0.948
SUB0046
Sugar phosphotransferase system (PTS), fructose family, IIA component.
 
 0.944
SUB0185
Sugar phosphotransferase system (PTS), fructose-specific family, IIA component.
  
 0.936
SUB0289
Putative mannitol-specific phosphotransferase system (PTS), IIBC component; Similar to the N-terminal region of Escherichia coli PTS system, mannitol-specific IIABC component MtlA UniProt:PTMA_ECOLI (EMBL:ECUW76) (637 aa) fasta scores: E()=6.9e-92, 51.502% id in 466 aa; Similar to the N-terminal region of SUB0997, 50.951% identity (51.940% ungapped) in 473 aa overlap (1-466:1-471).
   
 0.936
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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