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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB1236Competence protein CoiA-like family protein. (314 aa)    
Predicted Functional Partners:
pepB
Putative oligopeptidase.
       0.800
SUB0125
Conserved hypothetical protein.
  
     0.749
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.732
mecA
Adapter protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
 
   
 0.702
SUB1114
Conserved hypothetical protein.
  
     0.696
prsA1-2
Foldase protein PrsA 1 precursor; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
 
     0.660
SUB1234
Haloacid dehalogenase-like hydrolase.
  
    0.652
SUB1237
Major facilitator superfamily protein.
       0.616
SUB1091
Putative exported protein.
  
     0.587
SUB1473
ABC transporter protein EcsB.
  
     0.575
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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