Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (234 aa)    
Predicted Functional Partners:
SUB1443
Sugar phosphotransferase system (PTS), IIC component (fragment); Probable gene remnant. Similar to Lactobacillus casei LacE PTS system, lactose-specific IIBC component UniProt:PTLB_LACCA (EMBL:LCLACE) (577 aa) fasta scores: E()=1.8e-05, 23.342% id in 407 aa. CDS contains nonsense mutations after codon 86 (ochre) and 247 (opal) and lacks appropriate start and stop codons.
 0.998
glmM
Conserved hypothetical protein (pseudogene); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
 
 0.964
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.962
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.958
pmi
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.949
scrK2
Similar to SUB1542, 69.310% identity (69.310% ungapped) in 290 aa overlap (1-290:4-293).
    
 0.912
scrK1
Similar to SUB0308, 69.310% identity (69.310% ungapped) in 290 aa overlap (4-293:1-290).
    
 0.912
manL
Putative mannose-specific phosphotransferase system (PTS), IIAB component.
  
  
 0.874
SUB1652
ROK family protein.
 
   
 0.872
nanE
Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
     
 0.840
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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