close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB1268Putative membrane protein. (195 aa)    
Predicted Functional Partners:
SUB1269
GDSL-like lipase/acylhydrolase protein.
 
  
 0.972
SUB1270
Conserved hypothetical protein; Possible alternative translational start site after codon 4.
  
  
 0.822
argR-3
Putative repressor protein; Regulates arginine biosynthesis genes.
 
    0.707
SUB1114
Conserved hypothetical protein.
  
     0.688
SUB0125
Conserved hypothetical protein.
  
     0.659
SUB1473
ABC transporter protein EcsB.
  
     0.622
recN
Putative DNA repair protein; May be involved in recombinational repair of damaged DNA.
       0.601
prsA1-2
Foldase protein PrsA 1 precursor; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
 
     0.592
hlpA
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
       0.586
SUB1273
Hemolysin-like protein.
       0.580
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.