Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB1365Short chain dehydrogenase. (285 aa)    
Predicted Functional Partners:
SUB1366
Conserved hypothetical protein.
 
   
 0.872
SUB1364
Major facilitator superfamily protein.
 
   
 0.707
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.623
SUB1130
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.560
SUB1363
Major facilitator superfamily protein.
 
   
 0.555
SUB1367
LysR family regulatory protein; Belongs to the LysR transcriptional regulatory family.
 
  
 0.555
SUB1360
NADH:flavin oxidoreductase / NADH oxidase family protein.
 
  
 0.545
SUB1803
Full length CDS is similar to similar to Azoarcus sp. (strain EbN1) fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase UniProt:Q5P607_AZOSE (EMBL:CR555306) (671 aa) fasta scores: E()=4.2e-35, 28.299% id in 682 aa. N-terminal region is similar to Homo sapiens (Human) short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial precursor UniProt:HCDH_HUMAN (EMBL:HSAF1902) (314 aa) fasta scores: E()=3.3e-22, 37.687% id in 268 aa.
  
 0.484
fabD
Putative malonyl CoA-acyl carrier protein transacylase.
  
 
 0.445
SUB0860
Zinc-binding dehydrogenase.
 
 
 0.403
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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