STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB1383Sensor histidine kinase. (334 aa)    
Predicted Functional Partners:
SUB1382
Response regulator protein.
 
 0.999
SUB1384
Putative membrane protein.
 
  
 0.953
SUB0183
Response regulator protein.
 
 
 0.899
SUB1381
Cyclophilin type peptidyl-prolyl cis-trans isomerase protein.
  
    0.808
SUB1380
Putative S1 RNA binding domain protein.
       0.805
stk1
Serine/threonine-protein kinase.
  
  
 0.746
SUB1386
Putative protein phosphatase.
     
 0.708
SUB1387
Putative ribosomal RNA small subunit methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.701
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.660
priA
Putative primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.610
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.