STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB1398Putative permease. (445 aa)    
Predicted Functional Partners:
SUB1397
Putative D-beta-hydroxybutyrate dehydrogenase.
 
  
 0.817
atoD2
Acetate CoA-transferase alpha subunit 2.
 
  
 0.737
atoA2
Acetate CoA-transferase beta subunit 2.
 
  
 0.697
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
     
 0.680
atoB2
acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.592
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.517
SUB0201
Putative gluconokinase.
  
  
 0.487
SUB0199
6-phosphogluconate dehydrogenase family protein; Similar to the N-terminal regions of Saccharomyces cerevisiae (Baker's yeast) GND2 6-phosphogluconate dehydrogenase, decarboxylating 2 UniProt:6PG2_YEAST (492 aa) fasta scores: E()=3e-24, 37.209% id in 301 aa, and Escherichia coli 6-phosphogluconate dehydrogenase, decarboxylating Gnd UniProt:6PG9_ECOLI (468 aa) fasta scores: E()=3.1e-22, 36.333% id in 300 aa.
  
  
 0.485
SUB1393
LysR family regulatory protein; Belongs to the LysR transcriptional regulatory family.
 
     0.485
SUB1728
Putative glycerate kinase; Belongs to the glycerate kinase type-1 family.
  
  
 0.485
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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