Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (500 aa)    
Predicted Functional Partners:
glpO
Alpha-glycerophosphate oxidase.
 
 0.999
plsY
Putative membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.925
glpF1
Glycerol uptake facilitator protein 1; Similar to SUB0546, 56.466% identity (56.466% ungapped) in 232 aa overlap (1-232:1-232); Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.906
gla
Glycerol facilitator-aquaporin; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.866
htrA
Serine protease.
   
 0.800
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.777
pyrR
PyrR bifunctional protein [includes: pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
      
 0.744
SUB0236
Putative glucose-specific phosphotransferase system (PTS), IIABC component.
  
 
 0.722
SUB0830
Transcription antiterminator (pseudogene); HMMPfam hit to PF00874, PRD domain, score 2.1e-14.
  
 
 0.722
scrA
Putative sucrose-specific phosphotransferase system (PTS), IIABC component.
  
 
 0.722
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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