Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SUB1443Sugar phosphotransferase system (PTS), IIC component (fragment); Probable gene remnant. Similar to Lactobacillus casei LacE PTS system, lactose-specific IIBC component UniProt:PTLB_LACCA (EMBL:LCLACE) (577 aa) fasta scores: E()=1.8e-05, 23.342% id in 407 aa. CDS contains nonsense mutations after codon 86 (ochre) and 247 (opal) and lacks appropriate start and stop codons. (382 aa)    
Predicted Functional Partners:
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 0.998
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.968
nanE
Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
  
 0.952
glmM
Conserved hypothetical protein (pseudogene); Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
     
 0.950
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
     
 0.842
SUB0236
Putative glucose-specific phosphotransferase system (PTS), IIABC component.
 
   
 0.762
SUB0830
Transcription antiterminator (pseudogene); HMMPfam hit to PF00874, PRD domain, score 2.1e-14.
     
 0.716
scrA
Putative sucrose-specific phosphotransferase system (PTS), IIABC component.
     
 0.716
SUB1763
Sugar phosphotransferase system (PTS), IIABC component.
     
 0.716
SUB1444
Putative lipoprotein.
       0.613
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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