Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
copACopper-transporting ATPase. (743 aa)    
Predicted Functional Partners:
copZ-2
Putative copper chaperone.
  
 
 0.932
copY
Putative negative regulator of copper transport operon.
  
  
 0.863
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.715
copZ
Putative transposase (fragment); Probable gene remnant. Similar to the C-terminal region of Escherichia coli putative transposase InsK for insertion sequence element IS150 UniProt:INSK_ECOLI (EMBL:ECUW76) (283 aa) fasta scores: E()=4.7e-08, 34.615% id in 130 aa.
  
 
 0.666
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
   0.501
SUB1447
Haloacid dehalogenase-like hydrolase.
       0.439
SUB1468
Conserved hypothetical protein.
       0.437
SUB1467
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein.
       0.434
nusA
Putative N utilization substance protein A; Participates in both transcription termination and antitermination.
       0.424
SUB0614
Cation transporting ATPase.
 
 
0.414
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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