STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
copYPutative negative regulator of copper transport operon. (145 aa)    
Predicted Functional Partners:
copZ-2
Putative copper chaperone.
  
  
 0.976
copA
Copper-transporting ATPase.
  
  
 0.863
SUB0110
MarR-family regulatory protein.
     
 0.794
copZ
Putative transposase (fragment); Probable gene remnant. Similar to the C-terminal region of Escherichia coli putative transposase InsK for insertion sequence element IS150 UniProt:INSK_ECOLI (EMBL:ECUW76) (283 aa) fasta scores: E()=4.7e-08, 34.615% id in 130 aa.
  
  
 0.716
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
     
 0.705
nusA
Putative N utilization substance protein A; Participates in both transcription termination and antitermination.
 
     0.553
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
      
 0.528
SUB0112
ABC transporter permease protein.
     
 0.505
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.503
adcA
Zinc-binding protein AdcA precursor; Belongs to the bacterial solute-binding protein 9 family.
     
 0.487
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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