| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acoL | dnaJ | SUB1100 | SUB1503 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.481 |
| acoL | dnaK | SUB1100 | SUB1504 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.906 |
| acoL | groEL | SUB1100 | SUB1741 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | Putative surface-anchored protein (pseudogene); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.717 |
| acoL | groES | SUB1100 | SUB1742 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.441 |
| acoL | grpE | SUB1100 | SUB1505 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.519 |
| acoL | plr | SUB1100 | SUB1630 | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.555 |
| clpC | dnaJ | SUB1743 | SUB1503 | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.716 |
| clpC | dnaK | SUB1743 | SUB1504 | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.854 |
| clpC | groEL | SUB1743 | SUB1741 | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | Putative surface-anchored protein (pseudogene); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.761 |
| clpC | groES | SUB1743 | SUB1742 | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.819 |
| clpC | grpE | SUB1743 | SUB1505 | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.650 |
| clpL | dnaJ | SUB0776 | SUB1503 | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.801 |
| clpL | dnaK | SUB0776 | SUB1504 | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.916 |
| clpL | groEL | SUB0776 | SUB1741 | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | Putative surface-anchored protein (pseudogene); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.858 |
| clpL | groES | SUB0776 | SUB1742 | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.607 |
| clpL | grpE | SUB0776 | SUB1505 | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | GrpE protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.686 |
| dnaJ | acoL | SUB1503 | SUB1100 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24. | 0.481 |
| dnaJ | clpC | SUB1503 | SUB1743 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative stress response-related Clp ATPase; Belongs to the ClpA/ClpB family. | 0.716 |
| dnaJ | clpL | SUB1503 | SUB0776 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative ATP-dependent protease ATP-binding subunit ClpL; Belongs to the ClpA/ClpB family. | 0.801 |
| dnaJ | dnaK | SUB1503 | SUB1504 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
