Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflFormate acetyltransferase. (775 aa)    
Predicted Functional Partners:
pta
Putative phosphate acetyltransferase.
   
 
 0.970
adhE
Aldehyde-alcohol dehydrogenase 2 [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.962
pyk
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.962
pflC
Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.955
alsS
Acetolactate synthase; Belongs to the TPP enzyme family.
     
 0.949
pdhB
Putative pyruvate dehydrogenase E1 component, beta subunit.
   
 
 0.937
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
 0.934
acoL
HMMPfam hit to PF00689, Cation transporting ATPase, C-terminu, score 2.4e-24.
   
 
 0.930
pdhA
Putative pyruvate dehydrogenase E1 component, alpha subunit.
   
 
 0.924
pdhC
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 
 0.915
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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