Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SUB1570Putative beta-lactamase. (314 aa)    
Predicted Functional Partners:
SUB1571
Conserved hypothetical protein.
       0.835
SUB1197
Glycosyl hydrolase family protein.
  
 0.832
SUB1198
Glycosyl hydrolase family protein.
  
 0.776
SUB1572
Putative membrane protein.
       0.716
pepXP
Xaa-Pro dipeptidyl-peptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
 
   
 0.641
SUB1106
Putative esterase.
     
 0.602
dltB
Putative activated D-alanine transport protein; Could be involved in the transport of activated D-alanine through the membrane.
  
  
 0.485
dltA
D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
  
  
 0.482
SUB1515
Putative membrane protein.
     
 0.480
gla
Glycerol facilitator-aquaporin; Belongs to the MIP/aquaporin (TC 1.A.8) family.
       0.443
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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