Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUB1607LacI family regulatory protein. (335 aa)    
Predicted Functional Partners:
ptsH
Histidine-containing phosphocarrier protein (HPr).
   
 
 0.530
SUB1602
Putative sugar kinase.
 
  
 0.518
kduI
4-deoxy-l-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
  
  
 0.491
SUB0893
GntR family regulatory protein.
  
   
 0.476
SUB1607A
Hypothetical protein.
       0.466
SUB1603
Conserved hypothetical protein.
 
  
 0.427
idnO
Putative gluconate 5-dehydrogenase.
   
 
 0.422
SUB0041
GntR family regulatory protein.
  
   
 0.418
SUB0038
GntR family regulatory protein; Similar to the C-terminal Streptococcus agalactiae (serotype V) bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase] UniProt:PUR9_STRA5 (EMBL:AE014193) (515 aa) fasta scores: E()=9.7e-16, 85.000% id in 60 aa. Similar to the C-terminal region of SUB0030. Similar to the C-terminal region of SUB0030, 88.333% identity (88.333% ungapped) in 60 aa overlap (1-60:456-515).
  
   
 0.415
fruA-2
Putative fructose-specific phosphotransferase system (PTS), IIABC component.
     
 0.400
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.