STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
plrGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 0.999
tpi
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.998
fba
Fructose-bisphosphate aldolase.
  
 0.984
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.968
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.958
tkt2
Putative transketolase 2; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.952
pyk
Putative pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.943
gapN
Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.934
SUB1758
Putative transketolase subunit; Similar to the N-terminal region of Homo sapiens (Human) transketolase TKT UniProt:TKT_HUMAN (EMBL:HSTRANSKE) (623 aa) fasta scores: E()=9.4e-24, 34.286% id in 280 aa.
    
 0.908
SUB1757
Putative transketolase subunit; Similar to the C-terminal region of Homo sapiens (Human) transketolase TKT UniProt:TKT_HUMAN (EMBL:HSTRANSKE) (623 aa) fasta scores: E()=2.7e-17, 27.213% id in 305 aa.
    
 0.907
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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