STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SUB1676Sensor histidine kinase. (444 aa)    
Predicted Functional Partners:
fasA
Response regulator protein.
 
 
 0.983
SUB0498
Response regulator protein.
 
 
 0.982
SUB1675
Putative sensor kinase.
 
    
0.661
SUB1674
Putative sensor kinase (pseudogene); Similar to Streptococcus agalactiae histidine kinase RgfC UniProt:Q8L360_STRAG (EMBL:AF390107) (444 aa) fasta scores: E()=4.5e-24, 26.742% id in 445 aa. CDS contains a frameshift after codon 157.
 
    
0.551
SUB1799
Putative DNA-binding membrane protein (pseudogene); Predicted helix-turn-helix motif with score 2592.000, SD 8.02 at aa 16-37, sequence LSQEDLAEKIYVSRQTISNWEN.
  
     0.401
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.