srlE protein (Streptococcus uberis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

srlE

Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIBC component. (329 aa)

Predicted Functional Partners:

srlA

0.999

srlB

0.998

sorD

0.994

gutM

0.974

SUB1704

0.956

ptsH

0.905

pgi

0.516

SUB1720

0.500

dapH

0.457

SUB0158

0.418

Your Current Organism:

Streptococcus uberis

NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUB0158	srlB	SUB0158	SUB1700	Putative sugar-binding regulatory protein.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIA component.	0.458
SUB0158	srlE	SUB0158	SUB1701	Putative sugar-binding regulatory protein.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIBC component.	0.418
SUB1704	dapH	SUB1704	SUB1699	Transcription antiterminator.	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	0.426
SUB1704	gutM	SUB1704	SUB1703	Transcription antiterminator.	Glucitol operon activator protein.	0.965
SUB1704	pgi	SUB1704	SUB1706	Transcription antiterminator.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.665
SUB1704	sorD	SUB1704	SUB1705	Transcription antiterminator.	Sorbitol-6-phosphate 2-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.962
SUB1704	srlA	SUB1704	SUB1702	Transcription antiterminator.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIC2 component.	0.980
SUB1704	srlB	SUB1704	SUB1700	Transcription antiterminator.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIA component.	0.946
SUB1704	srlE	SUB1704	SUB1701	Transcription antiterminator.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIBC component.	0.956
SUB1720	srlE	SUB1720	SUB1701	Conserved hypothetical protein.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIBC component.	0.500
dapH	SUB1704	SUB1699	SUB1704	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Transcription antiterminator.	0.426
dapH	gutM	SUB1699	SUB1703	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Glucitol operon activator protein.	0.423
dapH	pgi	SUB1699	SUB1706	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.473
dapH	srlA	SUB1699	SUB1702	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIC2 component.	0.466
dapH	srlB	SUB1699	SUB1700	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIA component.	0.546
dapH	srlE	SUB1699	SUB1701	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	Putative glucitol/sorbitol-specific phosphotransferase system (PTS), IIBC component.	0.457
gutM	SUB1704	SUB1703	SUB1704	Glucitol operon activator protein.	Transcription antiterminator.	0.965
gutM	dapH	SUB1703	SUB1699	Glucitol operon activator protein.	Putative transferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	0.423
gutM	pgi	SUB1703	SUB1706	Glucitol operon activator protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.589
gutM	sorD	SUB1703	SUB1705	Glucitol operon activator protein.	Sorbitol-6-phosphate 2-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.955