| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SUB0651 | SUB1728 | SUB0651 | SUB1728 | Haloacid dehalogenase-like hydrolase; Similar to Shigella flexneri phosphoserine phosphatase SerB UniProt:SERB_ECOLI (EMBL:AE016993) (322 aa) fasta scores: E()=2.9e-24, 46.117% id in 206 aa, and to the full length Streptococcus thermophilus (strain ATCC BAA-250/LMG 18311) phosphoserine phosphatase SerB UniProt:Q5M3B3_STRTR (215 aa) fasta scores: E()=2.2e-46, 68.224% id in 214 aa. | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.443 |
| SUB0651 | glyA | SUB0651 | SUB0874 | Haloacid dehalogenase-like hydrolase; Similar to Shigella flexneri phosphoserine phosphatase SerB UniProt:SERB_ECOLI (EMBL:AE016993) (322 aa) fasta scores: E()=2.9e-24, 46.117% id in 206 aa, and to the full length Streptococcus thermophilus (strain ATCC BAA-250/LMG 18311) phosphoserine phosphatase SerB UniProt:Q5M3B3_STRTR (215 aa) fasta scores: E()=2.2e-46, 68.224% id in 214 aa. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.933 |
| SUB1398 | SUB1728 | SUB1398 | SUB1728 | Putative permease. | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.485 |
| SUB1398 | fruA-2 | SUB1398 | SUB0750 | Putative permease. | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | 0.680 |
| SUB1727 | SUB1728 | SUB1727 | SUB1728 | Putative sugar-specific permease, SgaT/UlaA family. | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.475 |
| SUB1727 | fruA-2 | SUB1727 | SUB0750 | Putative sugar-specific permease, SgaT/UlaA family. | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | 0.610 |
| SUB1727 | leuS | SUB1727 | SUB1729 | Putative sugar-specific permease, SgaT/UlaA family. | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.402 |
| SUB1728 | SUB0651 | SUB1728 | SUB0651 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Haloacid dehalogenase-like hydrolase; Similar to Shigella flexneri phosphoserine phosphatase SerB UniProt:SERB_ECOLI (EMBL:AE016993) (322 aa) fasta scores: E()=2.9e-24, 46.117% id in 206 aa, and to the full length Streptococcus thermophilus (strain ATCC BAA-250/LMG 18311) phosphoserine phosphatase SerB UniProt:Q5M3B3_STRTR (215 aa) fasta scores: E()=2.2e-46, 68.224% id in 214 aa. | 0.443 |
| SUB1728 | SUB1398 | SUB1728 | SUB1398 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Putative permease. | 0.485 |
| SUB1728 | SUB1727 | SUB1728 | SUB1727 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Putative sugar-specific permease, SgaT/UlaA family. | 0.475 |
| SUB1728 | birA | SUB1728 | SUB1213 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.451 |
| SUB1728 | fruA-2 | SUB1728 | SUB0750 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | 0.407 |
| SUB1728 | glyA | SUB1728 | SUB0874 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.406 |
| SUB1728 | gpmA | SUB1728 | SUB1263 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.903 |
| SUB1728 | leuS | SUB1728 | SUB1729 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.602 |
| SUB1728 | tadA | SUB1728 | SUB1707 | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | Putative deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.662 |
| birA | SUB1728 | SUB1213 | SUB1728 | BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.451 |
| fruA-2 | SUB1398 | SUB0750 | SUB1398 | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | Putative permease. | 0.680 |
| fruA-2 | SUB1727 | SUB0750 | SUB1727 | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | Putative sugar-specific permease, SgaT/UlaA family. | 0.610 |
| fruA-2 | SUB1728 | SUB0750 | SUB1728 | Putative fructose-specific phosphotransferase system (PTS), IIABC component. | Putative glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.407 |