Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hbd3-hydroxybutyryl-CoA dehydrogenase. (287 aa)    
Predicted Functional Partners:
thlA
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 0.997
atoB2
acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
 0.996
SUB1805
Putative acyl-CoA dehydrogenase.
 0.983
SUB1502
enoyl-CoA hydratase/isomerase family protein.
 0.979
atoA2
Acetate CoA-transferase beta subunit 2.
  
 
 0.939
atoD2
Acetate CoA-transferase alpha subunit 2.
  
 
 0.927
mvaS
3-hydroxy-3-methylglutaryl coenzyme A synthase.
     
  0.908
SUB1802
Putative fatty-acid CoA ligase.
 
  
 0.689
SUB1803
Full length CDS is similar to similar to Azoarcus sp. (strain EbN1) fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase UniProt:Q5P607_AZOSE (EMBL:CR555306) (671 aa) fasta scores: E()=4.2e-35, 28.299% id in 682 aa. N-terminal region is similar to Homo sapiens (Human) short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial precursor UniProt:HCDH_HUMAN (EMBL:HSAF1902) (314 aa) fasta scores: E()=3.3e-22, 37.687% id in 268 aa.
 
0.668
SUB1801
Putative coenzyme A transferase; Belongs to the 3-oxoacid CoA-transferase family.
 
   
 0.541
Your Current Organism:
Streptococcus uberis
NCBI taxonomy Id: 218495
Other names: S. uberis 0140J, Streptococcus uberis 0140J, Streptococcus uberis str. 0140J
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