Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A2G5CLU0Protein kinase domain-containing protein. (716 aa)    
Predicted Functional Partners:
A0A2G5FA63
Uncharacterized protein.
   
 
 0.812
A0A2G5CM44
WD_REPEATS_REGION domain-containing protein.
   
 
 0.798
A0A2G5DAX9
WD_REPEATS_REGION domain-containing protein.
   
 
 0.798
A0A2G5C8E0
Uncharacterized protein.
    
   0.724
A0A2G5F1V3
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.604
A0A2G5EJY3
Peptidyl-prolyl cis-trans isomerase.
    
  0.603
A0A2G5DAG6
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
    
   0.575
A0A2G5EAY4
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.531
A0A2G5ELD6
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.531
A0A2G5CEU4
Uncharacterized protein.
    
   0.527
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
Server load: low (8%) [HD]