Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
A0A2G5DF48Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (380 aa)    
Predicted Functional Partners:
A0A2G5FA63
Uncharacterized protein.
   
 0.953
A0A2G5D7D6
Serine/threonine-protein phosphatase.
    
 0.946
A0A2G5E9V5
BES1_N domain-containing protein.
     
 0.936
A0A2G5F5B8
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.855
A0A2G5F7N7
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.855
A0A2G5C474
Auxin response factor; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
    
 
 0.819
A0A2G5C524
Uncharacterized protein.
    
 0.791
A0A2G5F243
PB1 domain-containing protein.
    
 0.791
A0A2G5CT40
Uncharacterized protein.
    
 0.788
A0A2G5CQJ4
CYTH domain-containing protein.
    
 0.740
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
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