STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2G5DFB5Hat1_N domain-containing protein. (385 aa)    
Predicted Functional Partners:
A0A2G5CCT0
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.987
A0A2G5EIA7
WD_REPEATS_REGION domain-containing protein.
   
 0.945
A0A2G5F8K7
WD_REPEATS_REGION domain-containing protein.
   
 0.945
H6VVZ0_AQUCA
MSI1-like protein.
   
 0.945
A0A2G5EIH7
TPR_REGION domain-containing protein.
   
 
 0.944
A0A2G5CL81
ORC_WH_C domain-containing protein.
   
 
 0.925
A0A2G5CF49
AAA_16 domain-containing protein.
    
 
 0.919
A0A2G5C8J4
Uncharacterized protein.
   
 
 0.906
A0A2G5F6P9
Uncharacterized protein.
   
 
 0.896
A0A2G5CWL1
Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
    
 
 0.829
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.