Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A2G5EMI2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)    
Predicted Functional Partners:
A0A2G5EH85
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.968
A0A2G5DM31
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.945
A0A2G5EFC0
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.944
A0A2G5DM18
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 0.918
A0A2G5DGE6
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.916
A0A2G5FBK6
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.916
A0A2G5CXV1
Cyclin_C domain-containing protein.
   
 0.909
A0A2G5D256
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.909
A0A2G5EM78
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.909
A0A2G5DCX9
Uncharacterized protein.
   
 0.907
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
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