Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A2G5EY18Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (468 aa)    
Predicted Functional Partners:
A0A2G5ECX6
Uncharacterized protein.
    
 
 0.801
A0A2G5EEE3
J domain-containing protein.
    
 
 0.742
A0A2G5EPP6
J domain-containing protein.
    
 
 0.742
A0A2G5CRH8
Uncharacterized protein.
   
 
 0.732
A0A2G5DLK2
Uncharacterized protein.
   
 
 0.732
A0A2G5CSV6
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
    
 
 0.662
A0A2G5DF31
Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.
    
 
 0.581
A0A2G5DF44
Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.
    
 
 0.581
A0A2G5ELY8
Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.
    
 
 0.581
A0A2G5D5V2
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 
 0.577
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
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