Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A2G5F682Protein kinase domain-containing protein. (573 aa)    
Predicted Functional Partners:
A0A2G5EH85
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.917
A0A2G5DM31
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.904
A0A2G5DDD3
DNA helicase; Belongs to the MCM family.
   
 0.900
A0A2G5CCV2
Rhodanese domain-containing protein.
   
 0.895
A0A2G5EN12
DNA helicase; Belongs to the MCM family.
   
 0.886
A0A2G5C8J4
Uncharacterized protein.
   
 0.881
A0A2G5DM18
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 0.874
A0A2G5EAB4
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
   
 0.871
A0A2G5EFC0
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.871
A0A2G5CI20
Protein kinase domain-containing protein.
   
 0.869
Your Current Organism:
Aquilegia coerulea
NCBI taxonomy Id: 218851
Other names: A. coerulea, Aquilegia caerulea, Rocky Mountain columbine
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