node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A7J50_3297 | A7J50_3914 | A7J50_3297 | A7J50_3914 | Pfam:pfam01266 FAD dependent oxidoreductase. | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | 0.911 |
A7J50_3297 | A7J50_5376 | A7J50_3297 | A7J50_5376 | Pfam:pfam01266 FAD dependent oxidoreductase. | Pfam:pfam04268 Sarcosine oxidase, gamma subunit family. | 0.932 |
A7J50_3297 | A7J50_5377 | A7J50_3297 | A7J50_5377 | Pfam:pfam01266 FAD dependent oxidoreductase. | Sarcosine oxidase, alpha subunit; Pfam:pfam01571 Aminomethyltransferase folate-binding domain; Belongs to the GcvT family. | 0.973 |
A7J50_3297 | A7J50_5378 | A7J50_3297 | A7J50_5378 | Pfam:pfam01266 FAD dependent oxidoreductase. | Pfam:pfam04267 Sarcosine oxidase, delta subunit family. | 0.939 |
A7J50_3297 | A7J50_5379 | A7J50_3297 | A7J50_5379 | Pfam:pfam01266 FAD dependent oxidoreductase. | Sarcosine oxidase subunit beta; Pfam:pfam01266 FAD dependent oxidoreductase. | 0.910 |
A7J50_3297 | A7J50_5382 | A7J50_3297 | A7J50_5382 | Pfam:pfam01266 FAD dependent oxidoreductase. | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.900 |
A7J50_3297 | gcvP | A7J50_3297 | A7J50_4659 | Pfam:pfam01266 FAD dependent oxidoreductase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.913 |
A7J50_3297 | glyA | A7J50_3297 | A7J50_5054 | Pfam:pfam01266 FAD dependent oxidoreductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
A7J50_3297 | glyA-2 | A7J50_3297 | A7J50_5380 | Pfam:pfam01266 FAD dependent oxidoreductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
A7J50_3914 | A7J50_3297 | A7J50_3914 | A7J50_3297 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Pfam:pfam01266 FAD dependent oxidoreductase. | 0.911 |
A7J50_3914 | A7J50_5376 | A7J50_3914 | A7J50_5376 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Pfam:pfam04268 Sarcosine oxidase, gamma subunit family. | 0.931 |
A7J50_3914 | A7J50_5377 | A7J50_3914 | A7J50_5377 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Sarcosine oxidase, alpha subunit; Pfam:pfam01571 Aminomethyltransferase folate-binding domain; Belongs to the GcvT family. | 0.973 |
A7J50_3914 | A7J50_5378 | A7J50_3914 | A7J50_5378 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Pfam:pfam04267 Sarcosine oxidase, delta subunit family. | 0.939 |
A7J50_3914 | A7J50_5379 | A7J50_3914 | A7J50_5379 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Sarcosine oxidase subunit beta; Pfam:pfam01266 FAD dependent oxidoreductase. | 0.900 |
A7J50_3914 | A7J50_5382 | A7J50_3914 | A7J50_5382 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.900 |
A7J50_3914 | gcvP | A7J50_3914 | A7J50_4659 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.913 |
A7J50_3914 | glyA | A7J50_3914 | A7J50_5054 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
A7J50_3914 | glyA-2 | A7J50_3914 | A7J50_5380 | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
A7J50_5376 | A7J50_3297 | A7J50_5376 | A7J50_3297 | Pfam:pfam04268 Sarcosine oxidase, gamma subunit family. | Pfam:pfam01266 FAD dependent oxidoreductase. | 0.932 |
A7J50_5376 | A7J50_3914 | A7J50_5376 | A7J50_3914 | Pfam:pfam04268 Sarcosine oxidase, gamma subunit family. | Methyltryptophan oxidase; Pfam:pfam01266 FAD dependent oxidoreductase. | 0.931 |