STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_001571405_00701Unannotated protein. (316 aa)    
Predicted Functional Partners:
dphB
Unannotated protein; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
 
  
 0.691
GCA_001571405_00700
Unannotated protein; Belongs to the HMG-CoA reductase family.
 
     0.660
GCA_001571405_01695
Unannotated protein.
 
    0.609
taw1
Unannotated protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
 
  
 0.597
rpl22
Unannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
     0.583
GCA_001571405_01366
Unannotated protein.
  
  
 0.581
eif2b
Unannotated protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
  
  
 0.573
rps4e
Unannotated protein; Belongs to the eukaryotic ribosomal protein eS4 family.
  
     0.567
psmA
Unannotated protein; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
     0.545
rpl4
Unannotated protein; Forms part of the polypeptide exit tunnel.
  
     0.543
Your Current Organism:
Methanoculleus thermophilus
NCBI taxonomy Id: 2200
Other names: ATCC 33837, DSM 2373, M. thermophilus, Methaniculleus thermophilicus, Methanoculleus thermophilicum, Methanoculleus thermophilicus, Methanogenium frittonii, Methanogenium thermophilicum, Methanogenium thermophilum, OCM 174, strain CR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.