STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_001571405_01198Unannotated protein. (169 aa)    
Predicted Functional Partners:
GCA_001571405_00469
Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.997
GCA_001571405_00543
Unannotated protein; Belongs to the carbohydrate kinase PfkB family.
  
 0.997
guaAB
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
  
 0.997
GCA_001571405_02251
Unannotated protein.
  
 0.995
ade
Unannotated protein; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.993
guaAA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.986
surE
Unannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.985
GCA_001571405_01145
Unannotated protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
   
 
  0.976
GCA_001571405_01199
Unannotated protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
    0.959
hisF
Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.958
Your Current Organism:
Methanoculleus thermophilus
NCBI taxonomy Id: 2200
Other names: ATCC 33837, DSM 2373, M. thermophilus, Methaniculleus thermophilicus, Methanoculleus thermophilicum, Methanoculleus thermophilicus, Methanogenium frittonii, Methanogenium thermophilicum, Methanogenium thermophilum, OCM 174, strain CR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.